Uremine Mefenamic Acid Tablet

UREMINE®
Mefenamic Acid 500mg

 

COMPOSITION

Each tablet contains 500mg mefenamic Acid.

 

CLINICAL PHARMACOLOGY

Mefenamic acid is an anthranilic acid derivative nonsteroidal anti-inflammatory agent.

 

INDICATIONS

Mild to moderate pain including headache, dental pain, post-operative and post-partum pain, dymenorrhoea, in musculoskeletal and joint disorders such as osteoarthritis and rheumatoid arthritis (including juvenile arthritis) and menorrhagia.

 

CONTRA-INDICATIONS

Hypersensitivity to mefenamic acid, cross-sensitivity to aspirin and  other NSAID, intestinal ulceration or inflammatory bowel disease, avoid use in children below 14 years.

 

INTERACTION

Like any other NSAID, it interacts with other analgesic, avoid concomitant administration of two or more NSAID including Aspirin (increase side effects). Also interacts with other products such as Anticoagulants, probenecid, diuretic, beta blockers, corticosteroid, oral anti-diabetic, cyclosporins, digoxin.

 

PRECAUTIONS

Should be used with caution in patients with impaired renal or liver function, elderly with dehydration and renal disease, bronchial asthma or allergic disease and factors associated with peptic ulcers.

Co-administration with alcohol, aspirin or steroid may increase the risk of Gastro-intestinal bleeding.

 

WARNINGS

Occasionally, mefenamic acid has been associated with diarrhoea, rashes and heamolytic anaemia, treatment should therefore be discontinued if these occurs. May cause drowsiness. Blood count and liver function should be monitored during long-term therapy. It should be avoided in pregnancy and breast-feeding.

 

ADVERSE EFFECTS

Gastro-intestinal disturbances, diarrhoea or skin rash (discontinue) peptic ulceration, Gastro-intestinal bleeding, headache, drowsiness, dizziness, nervousness, visual disturbances, thrombocytopenia, haemolytic anaemia.

 

DOSAGE AND ADMINISTRATION

Adult by mouth
500mg 3 times daily preferably after food. Child over 6 months, 25mg/kg daily in divided doses for no longer than 7 days, except in juvenile arthritis.

 

PRESENTATION

Available in a box of 100 tablets. Each tablet contains 500mg mefenamic acid.

 

STORAGE INSTRUCTIONS

Store in cool place.

 

KEEP OUT OF THE REACH OF CHILDREN.

 

SHELF VALIDITY

3 Years

 

MANUFACTURED BY

Shandong Xier Kangtai Pharmaceutical Co., Ltd.

Private Economy Garden, Xinyan Town,

Yanzhou City, Shandong, China.

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