Atropine Sulphate Injection BP
It is a sterile colourless solution of Afropine Sulphate in water for is injections. Each ampoule contains Atropine sulphate 1mg.
Atropine is an antimuscarinic alkaloid with both central and peripheral actions. It first stimulates and then depress the central nervous system and has antispasmodic actions on smooth muscle and reduces secretions, especially salivary and bronchial secretions; It also reduces perspiration, but has little effect on biliary or pancreatic secretion.
Atropine Sulphate is chiefly used as spasmolytics. It has also been prescribed to alleviate the griping caused by vegetable laxative, and in the treatment of smooth muscle spasm in conditions such as renal and biliary colic. It has been used in the symptomatic treatment of idiopathic and postencephalitic parkinsonism.
DOSAGE & ADMINISTRATION
Usually in initial doses of 300 to 600ug intravenously, subsequently increased according to response. Atropine Sulphate 0.6 to 1.2mg is given by slowly intravenous injection in conjunction with neostigmine methylsulphate to reverse the effects of non-depolarising muscle relaxants. Suitable paediatric premedication doses of Atropine Sulphate are up to 65ug subcutaneously for premature infants, 100ug for premature infants, 200ug at 6 months to l year and 10 to 20ug per kg body – weight for older children.
Atropine Sulphate may lead to dryness of the mouth with difficulty in swallowing and talking, thirst, dilatation of the pupils (mydriasis) with loss of
accommodation (cycloplegia) and photophobia, flushing and dryness of the skin.
This agent is prohibited in use for glaucoma patient.
Ampoule of 1ml – Box of 10 or 100 ampoules.
Store in a cool, dry place, protected from light and heat.
NAFDAC Reg. No,: A4-8739
HUBEI TIANYAO PHARMACEUTICAL CO., LTD.
No.7 Dufu Block, Jianshe Road, Xiangfan Hubei China