Trypsin-Chymotrypsin Tablets 50,000 Units
“For Medical/Pharmacy Professionals Only”
DOSAGE FORM AND STRENGTH
Dosage Form: Tablet
Strength: 50,000 units
HISTORY OF ACTIVE INGREDIENTS
Chymotrypsin is a digestive enzyme component of pancreatic juice acting in the duodenum where it performs proteolysis, the breakdown of proteins and polypeptides.
Each enteric coated Tablet contains:
Trypsin-Chymotrypsin (6:1) Eq. to 500,000 Units of Proteolytic Enzyme Activity
Approved colour used.
Trypsin and Chymotrypsin are two different but related digestive enzymes produced and released by the pancreas. Both enzymes function within the intestine to help break down large protein molecules that we ingest in the foods we eat. Without this enzyme-aided digestion, you would be unable to get the essential amino acids required for tissue building and repair. Because these two enzymes break down proteins, they classified as proteases.
The cells in the pancreas synthesize and produce digestive enzymes that breakdown fats (lipases), starches (amylases), and proteins (proteases). Pancreatic proteases can be divided into several families of enzymes that differ in structure and catalytic effect in how they interact with the peptide bonds of proteins. These enzyme types of proteases are serine, threonine, cysteine, aspartic and metallo proteases. Trypsin and Chymotrypsin are two types of proteases in the serine family. Proteases are being used more and more medically and diagnostically in medicine for a multitude of health reasons including the treatment of pancreatic disease and cancer metastases. Trypsin and Chymotrypsin are originally synthesized in the pancreas in the inactive form of zymogen precursors (trypsinogen and chymotrypsinogen) for the purpose of stopping unnecessary cellular activity and controlling when and where enzyme activity occurs.
INDICATIONS AND USAGE
People take Chymotrypsin orally or as a shot to reduce redness and swelling associated with pockets of infection (abscesses), ulcers, surgery or traumatic injuries; and to help loosen phlegm in asthma, bronchitis, lung diseases, and sinus infections.
Cataract surgery, when used by a healthcare professional.
Burns: There is some evidence that Chymotrypsin might decrease tissue destruction in burn patients.
Hand Fractures: Taking Chymotrypsin by mouth seems to be effective for reducing redness and swelling associated with hand fractures.
Hypersensitivity to any of the Ingredients.
Tell your doctor or pharmacist before use if you are taking any regular medication on prescription or over the counter products. Rarely, Chymotrypsin might cause an allergic reaction when taken by mouth. Symptoms include itching, shortness of breath, swelling of the lips or throat, shock, loss of consciousness, and death.
SPECIAL PRECAUTIONS & WARNINGS
Glaucoma, as a complication of use of Chymotrypsin in cataract extractions pt, has occurred usually with 2-5 days after operation. There have been practically no indications of longer persisting glaucoma, from use of the enzyme.
Pregnancy and breast-feeding: Not enough is known about the use of Chymotrypsin during pregnancy and breast- feeding. Stay on the safe side and avoid use.
They split secondary amide or peptide bonds, carboxyIic or phenolic ester bonds & even carbon-carborn bonds. Their main function is to hydrolyze peptide bonds during the intestinal digestion of proteins.
DOSAGE AND ADMINISTRATION
As directed by the physician.
3 x 10 Tablets in a carton along with patient information leaflet.
Store at controlled room temperature below 25°C.
Protect from light & moisture and avoid exposure to excessive heat.
Keep all medicines away from children.
NAFDAC Reg. No.: 04-5309
Manufactured in India by
LABORATE PHARMACEUTICALS INDIA LTD.
51, Indi. Area, Paonta Sahib
HO.: E-11 IND. AREA PANIPAT-132103
EMBASSY PHARMACEUTICALS & CHEMICALS LTD.