Loxagyl Metronidazole Tablets and Suspension

LOXAGYL

Metronidazole Tablets

Metronidazole Benzoate Suspension

 

For use under medical or dental directions

 

INDICATION

In the oral treatment of all forms of amoebiasis, urogenital trichomoniasis, giardiasis, acute ulcerative gingivitis and Bacterial vaginosis (B.V.)

Loxagyl suspension is particularly recommended for children and adults who have difficulty in swallowing Loxagyl tablets. Loxagyl suspension is administered orally.

 

ADMINISTRATION

Tablets should be swallowed (without chewing) with half glassful of water. It is recommended that tablets be taken during or after meal. SHAKE THE BOTTLE BEFORE USE.

 

ADVERSE REACTIONS AND PRECAUTIONS

So far, no serious adverse reactions have been encountered. There have been occasional reports of an unpleasant taste in the mouth, furred tongue, nausea, vomiting (very rarely) and gastro-intestinal upset. Drowsiness, headache, skin rashes and pruritus have been reported, but rarely.

As with many other drugs, alcohol should be avoided during treatment with Loxagyl. Rare instances of slight and transient fall in blood pressure have been reported, it may therefore be advisable to lower the dosage of any anti-hypertensive drug which may be given concurrently.

Pregnant women tolerate metronidazole well and no adverse effect on their offspring.

Loxagyl can thus be given during the first three months of pregnancy and during lactation where the physician considers it essential; in these circumstances, the short high dosage regimens are not recommended.

 

PRESENTATION

Loxagyl tablets 200mg

Loxagyl tablets 400mg

Loxagyl Suspension 200mg/5ml.

 

RECOMMENDED DOSAGE

INDICATIONS Duration of Dosage in Days ADULTS and CHILDREN Over 10 years unless grossly under weight CHILDREN
7 to 10 years 3 to 7 years 1 to 3 years
Amoebiasis

(a) Invasive intestinal disease in susceptible subjects

 

 

5

20ml or 4(200mg) three times daily 10ml or 2(200mg) or 1(400mg) three times daily 5ml or 1(200mg) or 1/2(400mg) four times daily 5ml or 1(200mg) or 1/2 (400mg) three times daily
(b) Intestinal disease in less susceptible subjects and chronic amoebic hepatis  

 

5 – 10

10ml or 2(200mg) or 1(400mg) three times daily 5ml or 1(200mg) or 1/2(400mg) three times daily 2.5ml or 1/2(200mg) or 1/4(400mg) for times daily 2.5ml or 1/2(200mg) or 1/4(400mg) four times daily
(c) Symptomless cyst passers 5 10ml-20ml or 2-4(200mg) or 1-2(400mg) three times daily 5ml-10ml or 1-2(200mg) or 1/2-1(400mg) three times daily 2.5ml-5ml or 1/2-1(200mg) or 1/21/4(400mg) four times daily 2.5ml-5ml or 1/2-1(200mg) or 1/21/4(400mg) three times daily
Uro-genital Trichomoniasis

Where re-infection is likely, the consort should receive a similar course of treatment concurrently

7

 

or

 

2

5ml or 1(200mg) or 1/2(400mg) three times daily 2.5ml or 1/2(200mg) or 1/4(400mg) three times daily 2.5ml or 1/2(200mg) or 1/4(400mg) two times daily 1.25ml or 1/4(200mg) or 1/8(400mg) three times daily
20ml or 4(200mg) or 2(400mg) in the morning, 30ml or 6(200mg) or 3(400mg) in the evening
Glardiasis

A second course of treatment may be necessary for some patients two weeks after the end of the first course

 

 

 

3

50ml or 10(200mg) or 5(400mg) once daily 25ml or 5(200mg) or 21/2 (400mg) once daily 15ml or 3(200mg) or 11/2 (400mg) once daily 10ml or 2(200mg) or 1(400mg) once daily
Acute Ulcerative Gingivitis  

 

3

5ml or 1(200mg) or 1/2(400mg) three times daily 2.5ml or 1/2 (200mg) or 1/4(400mg) three times daily 2.5ml or 1/2 (200mg) or 1/4(400mg) twice daily 1.25ml or 1/4 (200mg) or 1/8(400mg) once daily
Baterial Vaginosis As for Trichomoniasis
  Immature children and babies weighing less than 11.34kg should receive proportionately smaller dosage, as advised by the physician.

 

Manufactured by

MAY & BAKER NIGERIA PLC

1, May & Baker Avenue, Off Idiroko Road,

(Opposite Convenant University)

Ota, Ogun State, Nigeria

http://www.may-baker.com

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