Kucam Piroxicam Capsules

KUCAM CAPSULES

PIROXICAM 20mg

 

COMPOSITION

Each capsule contains:

Piroxicam 20mg

 

INTRODUCTION

Piroxicam is a non-steroidal anti-inflammatory drug with best anti-arthritis activity. It inhibits the activity of prostaglandin synthetase enzyme, which is responsible for the biosynthesis of prostaglandins, the known mediators of inflammation. Piroxicam also inhibits collagen induced platelet aggregation.

 

INDICATIONS

Piroxicam is indicated for the acute and long term treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal disorders, acute gout, postoperative and post-traumatic pain and primary dysmenorrhoea.

 

DOSAGE AND ADMINISTRATION

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: 20mg daily as a single dose.

Acute musculoskeltal disorders: 40mg daily in single or divided doses for first 2 days, 20mg daily for the remaining 7 to 14 days.

Primary dysmenorrheal: 40mg daily for first 2 days, 20mg daily for 2 – 3 days thereafter.

 

ABSORPTION AND EXCRETION

Piroxicam is well absorbed from the gastro-intestinal tract, it is metabolized in the liver by hydroxylation and conjugation with glucuronic acid and excreted predominantly in the urine with smaller amounts in the faeces, less than 5% of the dose is excreted unchanged.

 

CONTRA-INDICATIONS

Piroxicam should be used with caution in patients with impaired renal function, in patients with cardiovascular disorders and in patients known to be hypersensitive to aspirin.

 

WARNING

Safety during pregnancy and lactation has not been established, dosage recommendations and indications for use in children under 12 years have not been established.

 

SIDE EFFECTS

Gastro-intestinal disturbances are the most common adverse effect. Peptic ulceration and gastro-intestinal bleeding have been rarely reported. Other side effects which have been reported include headache, dizziness, blurred vision, tinnitus, rashes, pruritus and oedema.

 

PRESENTATION

Pack of 10 blisters strips of 10 capsules, 1 blister strip of 10 capsules.

 

KEEP ALL MEDICINES OUT OF REACH OF CHILDREN

 

NAFDAC REG. NO.: B4-5956

 

For the use only of Medical Profession, Hospital or a Laboratory.

 

Manufactured by

SHANDONG XIER KANGTAI PHARM CO., LTD.

Private Economy Garden, Xinyan Town,

Yanzhou City, Shandong, China.

 

Marketed by

Pharmamax Nigeria Limited

(A member of KCH Group)

T1, Crown Centre, Crown Estate Lekki, Lagos-Nigeria

info@kch.com.ng

www.kch.com.ng

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